Of course you can. We live in a dynamically changing world where the volume of information increases on a colossal scale every day. Every day dozens of factors appear that can influence our opinions, beliefs, and worldview. It is normal if something becomes irrelevant. Such goals should be stopped immediately, and instead you should either set new ones or focus on accomplishing other goals that already exist.
In 2024, among my thirty-odd main goals, several became irrelevant over the course of the year, and roughly the same number of new ones appeared. They replaced the old ones in a fairly equivalent way in terms of time and financial cost.
Of course, it is important to strive for the percentage of changes to be minimal. In some cases it may even be normal if everything changes at once — although, frankly, I can barely imagine that. That is possible perhaps only in situations close to a personal life apocalypse. And even then, in my view, that is acceptable at best once or twice in a lifetime, but certainly not every year. If from year to year all your goals are completely replaced by entirely new ones — perhaps you are an impulsive person who changes their mind every other day and is unlikely to achieve anything significant with such an approach.
